Which is true during DNA replication?Group of answer choicesDNA ligase replaces the nucleotides in the RNA primer with DNA on the newly synthesised strands.RNA primers bound to both the leading and lagging strand are degraded by 5' - 3' exonucleases.DNA polymerase III synthesises the leading strand and DNA polymerase I synthesises the lagging strandPrimase is required to make primers on the lagging strand only
Question
Which is true during DNA replication?Group of answer choicesDNA ligase replaces the nucleotides in the RNA primer with DNA on the newly synthesised strands.RNA primers bound to both the leading and lagging strand are degraded by 5' - 3' exonucleases.DNA polymerase III synthesises the leading strand and DNA polymerase I synthesises the lagging strandPrimase is required to make primers on the lagging strand only
Solution
The correct answer is: DNA polymerase III synthesises the leading strand and DNA polymerase I synthesises the lagging strand.
Here's the step by step explanation:
- DNA replication begins at specific points in the genome called origins.
- The two DNA strands are separated by an enzyme called helicase, creating a replication fork.
- DNA polymerase III starts synthesising the leading strand. This is done continuously in the 5' to 3' direction.
- On the other hand, the lagging strand is synthesised discontinuously in short fragments known as Okazaki fragments. This is because DNA polymerase can only add nucleotides in the 5' to 3' direction.
- DNA polymerase I then replaces the RNA primers (which were necessary to start the replication process) with DNA.
- Finally, DNA ligase links the Okazaki fragments together to create a single, continuous strand.
So, the statement "DNA polymerase III synthesises the leading strand and DNA polymerase I synthesises the lagging strand" is true during DNA replication.
Similar Questions
Which is true during DNA replication?Group of answer choicesDNA ligase is the last step of the polymerisation reaction for the lagging strand, but is not used on the leading strand.DnaA binds to regions that are rich in AT as this purine-purine base pairing forms only two hydrogen bonds.The β sliding clamp prevents the dissociation of DNA polymerase III, increasing the length of DNA each polymerase can synthesise.DNA gyrase binds to and applies tension to the lagging strand.
Which statement about DNA replication is FALSE?View Available Hint(s)for Part EThe lagging strand is made of a series of pieces that must be joined together to make a continuous strand.DNA polymerase builds a new strand by adding DNA nucleotides one at a time.DNA ligase adds nucleotides to the lagging strand.Because the two strands of parental DNA run in opposite directions, the new strands must be made in different ways.The two strands of parental DNA are separated during DNA replication.
Which of the following statements is true regarding DNA replication?Choose 1 answer:Choose 1 answer:(Choice A) During lagging strand synthesis, ligase joins together multiple Okazaki fragments.ADuring lagging strand synthesis, ligase joins together multiple Okazaki fragments.(Choice B) During leading strand synthesis, DNA polymerase synthesizes short, discontinuous strands of DNA.BDuring leading strand synthesis, DNA polymerase synthesizes short, discontinuous strands of DNA.(Choice C) During lagging strand synthesis, topoisomerase separates complementary strands of DNA.CDuring lagging strand synthesis, topoisomerase separates complementary strands of DNA.(Choice D) During leading strand synthesis, a DNA primer helps initiate DNA synthesis.DDuring leading strand synthesis, a DNA primer helps initiate DNA synthesis.
During DNA replication:Ligase replaces RNA primers with DNA nucleotides.DNA polymerase III pairs Guanine with Cytosine.DNA polymerase I pairs Adenine with Cytosine.Okazaki fragments are created on the leading strand.
Which reaction in DNA replication is catalysed by DNA ligase?Group of answer choicesBase pairing of the template to the newly synthesised strandFormation of a phosphodiester linkage between two Okazaki fragmentsProof reading the template strand for errorsAddition of nucleotides to the lagging strand
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