Which statement about DNA replication is FALSE?View Available Hint(s)for Part EThe lagging strand is made of a series of pieces that must be joined together to make a continuous strand.DNA polymerase builds a new strand by adding DNA nucleotides one at a time.DNA ligase adds nucleotides to the lagging strand.Because the two strands of parental DNA run in opposite directions, the new strands must be made in different ways.The two strands of parental DNA are separated during DNA replication.
Question
Which statement about DNA replication is FALSE?View Available Hint(s)for Part EThe lagging strand is made of a series of pieces that must be joined together to make a continuous strand.DNA polymerase builds a new strand by adding DNA nucleotides one at a time.DNA ligase adds nucleotides to the lagging strand.Because the two strands of parental DNA run in opposite directions, the new strands must be made in different ways.The two strands of parental DNA are separated during DNA replication.
Solution
The false statement about DNA replication is: "DNA ligase adds nucleotides to the lagging strand."
This is incorrect because DNA ligase does not add nucleotides to the lagging strand. Instead, DNA ligase's function is to join the Okazaki fragments (short DNA sequences) on the lagging strand to create a continuous DNA strand. The enzyme that adds nucleotides to the lagging strand is DNA polymerase.
Similar Questions
Which statement about DNA replication is CORRECT?View Available Hint(s)for Part BDNA ligase helps assemble the leading strand.The leading strand is built continuously, and the lagging strand is built in pieces.The leading strand is one of the strands of parental DNA.The lagging strand is one of the strands of parental DNA.The lagging strand is built continuously.
Which is true during DNA replication?Group of answer choicesDNA ligase replaces the nucleotides in the RNA primer with DNA on the newly synthesised strands.RNA primers bound to both the leading and lagging strand are degraded by 5' - 3' exonucleases.DNA polymerase III synthesises the leading strand and DNA polymerase I synthesises the lagging strandPrimase is required to make primers on the lagging strand only
Which is true during DNA replication?Group of answer choicesDNA ligase is the last step of the polymerisation reaction for the lagging strand, but is not used on the leading strand.DnaA binds to regions that are rich in AT as this purine-purine base pairing forms only two hydrogen bonds.The β sliding clamp prevents the dissociation of DNA polymerase III, increasing the length of DNA each polymerase can synthesise.DNA gyrase binds to and applies tension to the lagging strand.
Which of the following statements is true regarding DNA replication?Choose 1 answer:Choose 1 answer:(Choice A) During lagging strand synthesis, ligase joins together multiple Okazaki fragments.ADuring lagging strand synthesis, ligase joins together multiple Okazaki fragments.(Choice B) During leading strand synthesis, DNA polymerase synthesizes short, discontinuous strands of DNA.BDuring leading strand synthesis, DNA polymerase synthesizes short, discontinuous strands of DNA.(Choice C) During lagging strand synthesis, topoisomerase separates complementary strands of DNA.CDuring lagging strand synthesis, topoisomerase separates complementary strands of DNA.(Choice D) During leading strand synthesis, a DNA primer helps initiate DNA synthesis.DDuring leading strand synthesis, a DNA primer helps initiate DNA synthesis.
Which of the following statements about DNA replication in bacteria is false?ANSWERDNA replication proceeds in only one direction around a circular chromosome.The leading strand is made continuously.DNA polymerase can only proceed in a 5’ to 3’ direction.DNA replication is semiconservative.
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