The patient's symptoms and test results suggest a diagnosis of pheochromocytoma, a rare tumor of the adrenal glands that can cause high blood pressure and excessive sweating.

Before surgery, it's important to manage the patient's high blood pressure and prevent a hypertensive crisis during the operation. This is typically done with alpha-adrenergic blocking drugs.

Phenoxybenzamine, a non-selective alpha-blocker, is often the drug of choice. It's started 10-14 days before surgery to achieve adequate alpha-adrenergic blockade.

After alpha-blockade is achieved, a beta-blocker such as propranolol can be added if necessary to control tachycardia. It's important to note that beta-blockers should not be started before alpha-blockers, as this can lead to unopposed alpha stimulation and a hypertensive crisis.

So, in this case, the patient should be given Phenoxybenzamine pre-operatively.

Question

The patient's symptoms and test results suggest a diagnosis of pheochromocytoma, a rare tumor of the adrenal glands that can cause high blood pressure and excessive sweating.

Before surgery, it's important to manage the patient's high blood pressure and prevent a hypertensive crisis during the operation. This is typically done with alpha-adrenergic blocking drugs.

Phenoxybenzamine, a non-selective alpha-blocker, is often the drug of choice. It's started 10-14 days before surgery to achieve adequate alpha-adrenergic blockade.

After alpha-blockade is achieved, a beta-blocker such as propranolol can be added if necessary to control tachycardia. It's important to note that beta-blockers should not be started before alpha-blockers, as this can lead to unopposed alpha stimulation and a hypertensive crisis.

So, in this case, the patient should be given Phenoxybenzamine pre-operatively.

Knowee AI · Accepted Answer

The patient's symptoms and test results suggest a diagnosis of pheochromocytoma, a rare tumor of the adrenal glands that can cause high blood pressure and excessive sweating.

Before surgery, it's important to manage the patient's high blood pressure and prevent a hypertensive crisis during the operation. This is typically done with alpha-adrenergic blocking drugs.

Phenoxybenzamine, a non-selective alpha-blocker, is often the drug of choice. It's started 10-14 days before surgery to achieve adequate alpha-adrenergic blockade.

After alpha-blockade is achieved, a beta-blocker such as propranolol can be added if necessary to control tachycardia. It's important to note that beta-blockers should not be started before alpha-blockers, as this can lead to unopposed alpha stimulation and a hypertensive crisis.

So, in this case, the patient should be given Phenoxybenzamine pre-operatively.

A 40-year old male presented with chronic hypertension, headaches, palpitations and excessive diaphoresis. Urine and plasma metanephrines were elevated. What drug will you give pre-operatively in this patient prior to surgery?

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