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Many factors contribute to the progression of CKD. Which of the following factor does NOT contribute to advance kidney disease?proteinuria angiotensin IIdecreased glomerular capillary permeabilitytubulointerstitial inflammation and fibrosis

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Many factors contribute to the progression of CKD. Which of the following factor does NOT contribute to advance kidney disease?proteinuria angiotensin IIdecreased glomerular capillary permeabilitytubulointerstitial inflammation and fibrosis

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Solution

The factor that does NOT contribute to advance kidney disease is decreased glomerular capillary permeability. This is because decreased glomerular capillary permeability would actually protect against kidney disease by preventing the leakage of proteins and other substances into the urine. On the other hand, proteinuria, angiotensin II, and tubulointerstitial inflammation and fibrosis are all factors that can contribute to the progression of chronic kidney disease (CKD).

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