Which of the following causes of proteinuria occurs due to overflow of protein, rather than glomerular or tubular injury?Question 14Answera.Multiple mylomab.Membranous nephropathyc.Lupus nephritisd.Focal segmental glomerulosclerosis
Question
Which of the following causes of proteinuria occurs due to overflow of protein, rather than glomerular or tubular injury?Question 14Answera.Multiple mylomab.Membranous nephropathyc.Lupus nephritisd.Focal segmental glomerulosclerosis
Solution
The cause of proteinuria that occurs due to overflow of protein, rather than glomerular or tubular injury, is Multiple Myeloma.
Here's why:
Multiple Myeloma is a type of blood cancer that occurs when malignant plasma cells in the bone marrow produce abnormal proteins (monoclonal proteins) that can pass into the urine. This is known as overflow proteinuria because the proteins are produced in such large amounts that they 'overflow' into the urine, rather than being caused by damage to the kidneys themselves.
On the other hand, Membranous nephropathy, Lupus nephritis, and Focal segmental glomerulosclerosis are all conditions that cause proteinuria due to damage to the glomeruli or tubules in the kidneys.
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