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Explain the causative factors and pathophysiology in allergic asthma

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Explain the causative factors and pathophysiology in allergic asthma

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Allergic asthma is a type of asthma that is triggered by allergens in the environment. It is the most common form of asthma and affects about 60% of people with asthma.

  1. Causative Factors: The main causative factors of allergic asthma are allergens. These can include dust mites, pet dander, pollen, mold, and cockroach waste. When a person with allergic asthma inhales these allergens, their immune system overreacts and triggers an asthma attack. Other factors that can contribute to allergic asthma include a family history of allergies or asthma, having another allergic condition like atopic dermatitis or allergic rhinitis, and exposure to tobacco smoke or air pollution.

  2. Pathophysiology: The pathophysiology of allergic asthma involves an overactive immune response. When a person with allergic asthma inhales an allergen, their immune system recognizes it as a threat and produces antibodies called Immunoglobulin E (IgE). These antibodies bind to the allergen and trigger the release of chemicals like histamine from mast cells. This causes inflammation and swelling in the airways, leading to symptoms of asthma like wheezing, shortness of breath, chest tightness, and coughing. Over time, this inflammation can cause permanent changes in the structure of the airways, leading to more severe and persistent asthma symptoms.

In summary, allergic asthma is caused by an overreaction of the immune system to allergens in the environment, leading to inflammation and swelling in the airways. This can cause symptoms like wheezing, shortness of breath, and coughing, and over time can lead to more severe and persistent asthma symptoms.

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