> ndividual with allergic or atopic asthma, all of the following events would occur within minutes of exposure to an antigen, EXCEPT: > 1. **Increased levels of plasma cells in the airway** 2. Antigen interaction with IgE antibodies 3. Mast cell degranulation 4. Release of mediators such as histamine, prostaglandins and leukotrienes
Question
ndividual with allergic or atopic asthma, all of the following events would occur within minutes of exposure to an antigen, EXCEPT:
- Increased levels of plasma cells in the airway
- Antigen interaction with IgE antibodies
- Mast cell degranulation
- Release of mediators such as histamine, prostaglandins and leukotrienes
Solution
The correct answer is 1. Increased levels of plasma cells in the airway.
Here's why:
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Increased levels of plasma cells in the airway: This process does not occur within minutes of exposure to an antigen in an individual with allergic or atopic asthma. Plasma cells are responsible for producing antibodies, and this process takes more time, not just minutes after exposure to an antigen.
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Antigen interaction with IgE antibodies: This is one of the first steps in an allergic reaction. The antigen (allergen) is recognized and bound by IgE antibodies, which are attached to mast cells.
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Mast cell degranulation: After the antigen interacts with the IgE antibodies, the mast cells are triggered to degranulate, releasing their contents.
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Release of mediators such as histamine, prostaglandins and leukotrienes: These are the contents released by the mast cells during degranulation. They cause the symptoms associated with an allergic reaction, such as inflammation, bronchoconstriction, and mucus production.
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