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Which of the following turns off an RTK signaling pathway by shutting off the receptor?Group of answer choicesKinasesPhosphatasesGAPsGEFs

Question

Which of the following turns off an RTK signaling pathway by shutting off the receptor?Group of answer choicesKinasesPhosphatasesGAPsGEFs

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Solution

The RTK (Receptor Tyrosine Kinase) signaling pathway can be turned off by Phosphatases. Phosphatases are enzymes that remove a phosphate group from a protein in a process called dephosphorylation. In the context of RTK signaling, phosphatases can shut off the receptor by removing the phosphate groups added by kinases, thus inactivating the receptor and turning off the signaling pathway.

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