The kinase that phosphorylates a receptor tyrosine kinase (RTK) is:Group of answer choicesRasMAP kinaseRTK itselfAkt
Question
The kinase that phosphorylates a receptor tyrosine kinase (RTK) is:Group of answer choicesRasMAP kinaseRTK itselfAkt
Solution
The kinase that phosphorylates a receptor tyrosine kinase (RTK) is the RTK itself. This is because RTKs are capable of autophosphorylation - a process where they add a phosphate group to themselves. This happens when a specific ligand binds to the RTK, causing it to form a dimer with another RTK. The dimerization activates the kinase domain, which then phosphorylates the tyrosine residues on the other RTK in the dimer.
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