A 56-year-old man with mitral valve prolapse requires a dental procedure. He is allergic to penicillins. An appropriate oral prophylactic antimicrobial drug for this patient is: a. doxycycline b. gentamicin c. aztreonam d. ciprofloxacin e. azithromycin
Question
A 56-year-old man with mitral valve prolapse requires a dental procedure. He is allergic to penicillins. An appropriate oral prophylactic antimicrobial drug for this patient is: a. doxycycline b. gentamicin c. aztreonam d. ciprofloxacin e. azithromycin
Solution
The correct answer is e. azithromycin.
Here's why:
Patients with mitral valve prolapse who require a dental procedure are at risk for endocarditis, an infection of the inner lining of the heart. To prevent this, they are often given prophylactic antibiotics before the procedure.
The American Heart Association recommends oral amoxicillin for such patients. However, this patient is allergic to penicillins, so an alternative is needed.
Azithromycin is a macrolide antibiotic that is commonly used as an alternative to penicillin in patients with penicillin allergy. It is effective against a wide range of bacteria, including those that can cause endocarditis.
Doxycycline, gentamicin, aztreonam, and ciprofloxacin are also antibiotics, but they are not the first choice for prophylaxis in this situation. Gentamicin is not typically given orally, aztreonam is used for gram-negative bacteria, and ciprofloxacin is a broad-spectrum antibiotic that is not typically used for this purpose. Doxycycline could potentially be used as an alternative, but azithromycin is generally preferred.
Similar Questions
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Antibiotics with the root "cillin" in their names, interfere with bacterial cell .
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