Antibiotics with the root "cillin" in their names, interfere with bacterial cell .
Question
Antibiotics with the root "cillin" in their names, interfere with bacterial cell .
Solution
Antibiotics with the root "cillin" in their names, such as penicillin and amoxicillin, interfere with bacterial cell wall synthesis. Here's a step-by-step explanation:
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These antibiotics belong to a group called beta-lactam antibiotics. They contain a beta-lactam ring in their molecular structure.
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This beta-lactam ring is able to bind to enzymes in the bacterial cell called penicillin-binding proteins (PBPs).
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PBPs are responsible for the final step of the synthesis of peptidoglycan, which is a major component of the bacterial cell wall.
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When the beta-lactam antibiotics bind to the PBPs, they inhibit the function of these enzymes.
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This prevents the synthesis of peptidoglycan, leading to a weak cell wall.
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The bacterial cell wall provides the bacteria with structural integrity and protection. Without a fully formed cell wall, the bacteria can easily be destroyed or lysed.
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Therefore, by interfering with the synthesis of the bacterial cell wall, "cillin" antibiotics can effectively kill bacteria or prevent them from growing and multiplying.
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