An electrophoretic separation of lactate dehydrogenase isoenzyme that demonstrates elevation in LD-1 greater than LD-2 could be indicative of:
Question
An electrophoretic separation of lactate dehydrogenase isoenzyme that demonstrates elevation in LD-1 greater than LD-2 could be indicative of:
Solution
An elevation in LD-1 greater than LD-2 in an electrophoretic separation of lactate dehydrogenase isoenzyme could be indicative of a myocardial infarction, also known as a heart attack.
Here's a step-by-step explanation:
-
Lactate dehydrogenase (LDH) is an enzyme found in almost all body tissues, but only released into the bloodstream when there's tissue damage.
-
LDH is made up of five isoenzymes, which can be separated by electrophoresis. These isoenzymes are LD-1, LD-2, LD-3, LD-4, and LD-5.
-
Under normal conditions, the LD-1 level is lower than the LD-2 level in the blood.
-
However, when a heart attack occurs, heart cells are damaged and release their LDH. The LDH from heart cells is primarily LD-1.
-
Therefore, after a heart attack, the LD-1 level in the blood can become higher than the LD-2 level. This is known as a "flipped LDH pattern" and is a strong indicator of a recent heart attack.
-
So, an electrophoretic separation of lactate dehydrogenase isoenzyme that shows an elevation in LD-1 greater than LD-2 could be indicative of a myocardial infarction.
Similar Questions
An electrophoretic separation of lactate dehydrogenase isoenzyme that demonstrates elevation in LD-1 greater than LD-2 could be indicative of:Please select the single best answer A normal LD isoenzyme pattern Hemolysis Pancreatitis Hepatic injury
A dehydrogenase enzyme belongs to which classification?Question 11Select one:a.hydrolaseb.oxidoreductasec.ligased.lyase
What is the function of LD in the body?Please select the single best answer Interconversion of lactate to glucose Non-reversible conversion of pyruvate to lactate Interconversion of lactate and pyruvate Conversion of glucose to lactate
Lactate dehydrogenase in the liver:Group of answer choicesoxidises lactate to pyruvatereduces lactate to pyruvateoxidises pyruvate to lactatereduces pyruvate to lactate
Factors influencing enzymatic activity which enzymes undergo denaturation can beGroup of answer choicesall of the abovechemicalstemperaturesaltpH
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.