An electrophoretic separation of lactate dehydrogenase isoenzyme that demonstrates elevation in LD-1 greater than LD-2 could be indicative of:Please select the single best answer A normal LD isoenzyme pattern Hemolysis Pancreatitis Hepatic injury
Question
An electrophoretic separation of lactate dehydrogenase isoenzyme that demonstrates elevation in LD-1 greater than LD-2 could be indicative of:Please select the single best answer A normal LD isoenzyme pattern Hemolysis Pancreatitis Hepatic injury
Solution
The elevation of LD-1 over LD-2 in an electrophoretic separation of lactate dehydrogenase isoenzyme could be indicative of a myocardial infarction (heart attack). This is because LD-1 is found in heart muscle and red blood cells, while LD-2 is found in white blood cells and the lungs. When there is damage to the heart muscle, such as in a heart attack, LD-1 is released into the bloodstream, causing an increase in its levels. Therefore, an elevation in LD-1 greater than LD-2 is often used as a marker for heart damage. However, this is not a definitive test and other factors need to be considered for a proper diagnosis.
Similar Questions
What is the function of LD in the body?Please select the single best answer Interconversion of lactate to glucose Non-reversible conversion of pyruvate to lactate Interconversion of lactate and pyruvate Conversion of glucose to lactate
A dehydrogenase enzyme belongs to which classification?Question 11Select one:a.hydrolaseb.oxidoreductasec.ligased.lyase
You will need to give some background information on LDH, enough to make thereader familiar with the enzyme you are working with.You will need to do some searching on PubMed for this. Also, don’t be afraid to usearticles that were written many years ago; most mammalian enzymes were originallypurified decades ago.A part of your introduction could be to discuss:1- The structure of LDH. Knowing the catalytic site, the composition of amino acidshaving figures will be great and will help you later on your discussion.2- The importance of LDH as a biomarker in many diseases. Be innovative since thispart is relevant for you as future doctor.3- Inhibition of LDH (different types of inhibitors) and the importance of drug designin medicine in general of for LDH as biomarker specifically
Factors influencing enzymatic activity which enzymes undergo denaturation can beGroup of answer choicesall of the abovechemicalstemperaturesaltpH
Lactate dehydrogenase in the muscle:Group of answer choicesoxidises lactate to pyruvatereduces pyruvate to lactatereduces lactate to pyruvateoxidises pyruvate to lactate
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