What is the function of LD in the body?Please select the single best answer Interconversion of lactate to glucose Non-reversible conversion of pyruvate to lactate Interconversion of lactate and pyruvate Conversion of glucose to lactate

Lactate dehydrogenase in the muscle:Group of answer choicesoxidises lactate to pyruvatereduces pyruvate to lactatereduces lactate to pyruvateoxidises pyruvate to lactate

An electrophoretic separation of lactate dehydrogenase isoenzyme that demonstrates elevation in LD-1 greater than LD-2 could be indicative of:

In human skeletal muscle, during anaerobic exercise the pyruvate formed from glycolysis is converted to lactate. Why is this reaction important?Question 4

The lac operon system, first described by Jacob and Monod, regulates lactose metabolism in . The is composed of a gene encoding a protein that normally keeps this operon in the position. Within the , the repressor binds to the , blocking transcription of structural genes needed for lactose metabolism. When is added to a cell's environment, it binds the repressor freeing the operator segment of the DNA. is now able to bind to the promoter, transcribing all three structural genes needed for lactose catabolism. When lactose again becomes depleted in the cell, the repressor binds to the operator blocking additional synthesis of enzymes from the .

You will need to give some background information on LDH, enough to make thereader familiar with the enzyme you are working with.You will need to do some searching on PubMed for this. Also, don’t be afraid to usearticles that were written many years ago; most mammalian enzymes were originallypurified decades ago.A part of your introduction could be to discuss:1- The structure of LDH. Knowing the catalytic site, the composition of amino acidshaving figures will be great and will help you later on your discussion.2- The importance of LDH as a biomarker in many diseases. Be innovative since thispart is relevant for you as future doctor.3- Inhibition of LDH (different types of inhibitors) and the importance of drug designin medicine in general of for LDH as biomarker specifically