Which of the following is incorrect about drug-drug interactions?Group of answer choicesDrug-drug interactions can be exploited to boost drug concentrations and improve patient complianceThe genetics of the individual do not influence the risk of a drug-drug interactionNatural products, herbal supplements and food can potentially interact with drugsDrug-drug interactions are not predictableAll of the above

Which statement is true about drug-drug interactions?Group of answer choicesThe concentration of the object drug increases when the precipitant drug is an inhibitorThe concentration of the object drug increases when the precipitant drug is an inducerThe pharmacodynamic effects of the object drug cannot be altered by a drug-drug interactionAll of the aboveNone of the above

Which one of the following statements about genetic differences (polymorphisms) influencing drug behaviour is INCORRECT?Group of answer choicesPolymorphisms in a gene encoding a protein may have no consequences for protein function.Polymorphisms in enzymes that metabolise drugs are rare.Polymorphisms in a receptor gene might lead to changes in drug binding to that receptor.Polymorphisms in a receptor gene might lead to changes in the ability of the receptor to initiate cell activation following drug binding.

Which of the following would not be considered a beneficial characteristic when choosing a new antimicrobial drug?ANSWERExtended stability in the human bodyHigh selective toxicityNarrow therapeutic indexLow drug interactions

Determine the CORRECT terms used in drug-receptor interactions with the appropriate responses. A. Difference in intrinsic abilities of two drugs bound to the same receptor to elicit an the effect is the Relative Potency. TRUE/FALSE B. Relative Affinity shows the relative position of drugs along the dose-response curve axis. TRUE/FALSE C. The comparison of the amount that causes therapeutic effect to the amount that causes toxicity is the Therapeutic Index. TRUE/FALSE D. Relative Efficacy determines the concentration of drug required to produce a certain degree of rightward shift in the presence of its antagonist. TRUE/FALSE E. Therapeutic Window is used to define limits of drug concentrations that provide therapeutic efficacy with minimal toxicity. TRUE/FALSE

Which of the following are true statements regarding antimicrobial resistance?Group of answer choicesBoth appropriate and inappropriate use of antibiotics select for resistanceUse of antimicrobials in agriculture accounts for the minority of antibiotic use in the USAPhysicians are solely responsible for the antibiotic resistance crisisAll of the above are true