Determine the CORRECT terms used in drug-receptor interactions with the appropriate responses. A. Difference in intrinsic abilities of two drugs bound to the same receptor to elicit an the effect is the Relative Potency. TRUE/FALSE B. Relative Affinity shows the relative position of drugs along the dose-response curve axis. TRUE/FALSE C. The comparison of the amount that causes therapeutic effect to the amount that causes toxicity is the Therapeutic Index. TRUE/FALSE D. Relative Efficacy determines the concentration of drug required to produce a certain degree of rightward shift in the presence of its antagonist. TRUE/FALSE E. Therapeutic Window is used to define limits of drug concentrations that provide therapeutic efficacy with minimal toxicity. TRUE/FALSE

Dose-response data was collected during the testing of drugs A and B. Drug B markedly decreases the efficacy of drug A and even increases the dose of drug A, So, drug B is:a.Non-competitive antagonistb.Partial agonistc.Inverse agonistd.Competitive antagonist

Which of the following parameters is used to indicate the ability of a drug to produce the desired therapeutic effect relative to a toxic effect? * (a) Potency (B) Intrinsic activity (C) Therapeutic Index (D) Efficacy (e) Bioavailability

Which statement is true about drug-drug interactions?Group of answer choicesThe concentration of the object drug increases when the precipitant drug is an inhibitorThe concentration of the object drug increases when the precipitant drug is an inducerThe pharmacodynamic effects of the object drug cannot be altered by a drug-drug interactionAll of the aboveNone of the above

The clinical application of drug-receptor interactions include: A. assessment and classification of new agonists TRUE/FALSE B. define ligand activity and selectivity in normal and diseased tissues TRUE/FALSE C. identify novel chemical structures/drugs that interact with receptors TRUE/FALSE D. identification and characterization of receptors transfected into cell lines TRUE/FALSE E. study receptor dynamics and localization TRUE/FALSE

Dose-response curves can be used to: A. determine if a drug produces a certain desired effect TRUE/FALSE B. estimate the relative safety of a drug TRUE/FALSE C. compare a particular drug with its congeners TRUE/FALSE D. determine the dose required to produce effect by a drug TRUE/FALSE E. assess the efficacy and effectiveness of drugs TRUE/FALSE