Knowee
Questions
Features
Study Tools

A clinical trial wishes to determine whether mastectomy is more effective than chemotherapy in the treatment of breast cancer. Which option best describes a surrogate outcome for this trial?Question 4Select one:a.Mortalityb.Mental health statusc.Tumour graded.Nausea

Question

A clinical trial wishes to determine whether mastectomy is more effective than chemotherapy in the treatment of breast cancer. Which option best describes a surrogate outcome for this trial?Question 4Select one:a.Mortalityb.Mental health statusc.Tumour graded.Nausea

🧐 Not the exact question you are looking for?Go ask a question

Solution

A surrogate outcome in a clinical trial is a measure of effect of a specific treatment that may correlate with a real clinical endpoint but does not necessarily have a guaranteed relationship. The surrogate endpoint is often used in clinical trials as it may be measured more easily or more rapidly than the clinical endpoint.

In the context of a clinical trial comparing mastectomy and chemotherapy in the treatment of breast cancer, a surrogate outcome could be the tumor grade. The tumor grade is a measure of the aggressiveness of the cancer, and changes in the tumor grade could potentially indicate the effectiveness of the treatment.

So, the best answer would be:

c. Tumor grade

This problem has been solved

Similar Questions

If you are studying the rate of breast cancer, which of the following events would affect a participant’s person-time? (You must choose all that apply to receive credit for this question; no partial credit will be awarded.)1 pointparticipant decides to no longer participate in the studydeathpatient undergoes a double mastectomy diagnosis with uterine cancerloss to follow-up

Select the reasons to conduct pre-clinical trials.

You wish to investigate the factors that predispose one to breast cancer.  Which of the following is likely NOT the best option for carrying out this study?Designed experimentObservational studyRetrospective study

Which of the following statements is true about surrogate endpoints?Question 5Select one:a.Are only used in studies that have mortality as an outcomeb.They prolong the time taken to complete the studyc.They cannot be used to measure secondary outcomesd.They capture a clinical endpoint, without actually measuring it

Question 1Clinical trials involve

1/1

Upgrade your grade with Knowee

Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.