In staphylococcal skin infection there is neutrophilic infiltrate causing tissue damage. Thetissue damage is most likely caused due to:Select one:a. Release of cytosolic calciumb. Release of cytochrome cc. Activation of caspasesd. Generation of superoxideClear my choice
Question
In staphylococcal skin infection there is neutrophilic infiltrate causing tissue damage. Thetissue damage is most likely caused due to:Select one:a. Release of cytosolic calciumb. Release of cytochrome cc. Activation of caspasesd. Generation of superoxideClear my choice
Solution
The tissue damage in staphylococcal skin infection is most likely caused by the generation of superoxide (option d).
Here's a step-by-step explanation:
- Staphylococcus bacteria infect the skin, causing an immune response.
- Neutrophils, a type of white blood cell, are part of the body's first line of defense and respond to the infection.
- These neutrophils produce superoxide, a reactive oxygen species, to kill the bacteria.
- However, the generation of superoxide can also cause collateral damage to the surrounding tissues, leading to tissue damage.
So, the most likely cause of tissue damage in staphylococcal skin infection is the generation of superoxide by neutrophils.
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