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Which of the following is (are) associated with the activation of transcription?Group of answer choicesChromatin remodeling.Histone acetylation.RNA polymerase recruited to the promoter.Transcription factors recruited to the (eukaryotic) promoter.All of the above.

Question

Which of the following is (are) associated with the activation of transcription?Group of answer choicesChromatin remodeling.Histone acetylation.RNA polymerase recruited to the promoter.Transcription factors recruited to the (eukaryotic) promoter.All of the above.

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Solution

All of the above.

Here's why:

  1. Chromatin remodeling: This process makes the DNA accessible to the transcription machinery, thus activating transcription.

  2. Histone acetylation: This modification of histones reduces their positive charge, weakening the interaction between the histones and the DNA. This makes the DNA more accessible for transcription.

  3. RNA polymerase recruited to the promoter: The promoter is the region of DNA that initiates transcription of a particular gene. RNA polymerase must bind to the promoter to start transcription.

  4. Transcription factors recruited to the (eukaryotic) promoter: Transcription factors are proteins that control the rate of transcription by binding to specific DNA sequences (promoters). Their recruitment to the promoter is a key step in the activation of transcription.

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