Which of the following is (are) associated with the activation of transcription?Group of answer choicesChromatin remodeling.Histone acetylation.RNA polymerase recruited to the promoter.Transcription factors recruited to the (eukaryotic) promoter.All of the above.
Question
Which of the following is (are) associated with the activation of transcription?Group of answer choicesChromatin remodeling.Histone acetylation.RNA polymerase recruited to the promoter.Transcription factors recruited to the (eukaryotic) promoter.All of the above.
Solution
All of the above.
Here's why:
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Chromatin remodeling: This process makes the DNA accessible to the transcription machinery, thus activating transcription.
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Histone acetylation: This modification of histones reduces their positive charge, weakening the interaction between the histones and the DNA. This makes the DNA more accessible for transcription.
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RNA polymerase recruited to the promoter: The promoter is the region of DNA that initiates transcription of a particular gene. RNA polymerase must bind to the promoter to start transcription.
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Transcription factors recruited to the (eukaryotic) promoter: Transcription factors are proteins that control the rate of transcription by binding to specific DNA sequences (promoters). Their recruitment to the promoter is a key step in the activation of transcription.
Similar Questions
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Which of the following processes may result in the silencing or activation of genes?Group of answer choicesHistone AcetylationHistone PhosphorylationHistone MethylationHistone RibosylationNone of the above
Which of the following is most likely to increase expression of a particular gene? Group of answer choicesa mutation in a silencerrecruitment of histone methyltransferasesrecruitment of histone deacetylasescis regulation by a lncRNA
The promoter: A) Is an RNA sequence necessary for activating the transcription of a gene B) Is an RNA sequence necessary for activating translation C) Is a DNA sequence necessary for regulating the transcription of a gene D) Is the site of initiation of gene transcription E) Is a protein factor necessary for activating gene transcription
How does histone acetylation activate transcription in eukaryotes?Group of answer choicesby increasing the affinity of histone for DNAby recruiting other components of the transcriptional machineryby inhibiting the active remodeling of the chromatin structureall of the abovenone of the above
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