A 52-year-old man complained to his physician of acute pain at the base of his right big toe. The man, who had been working as a painter for 15 years, was recently diagnosed with essential hypertension and started an antihypertensive therapy one month ago. A lab test showed a plasma uric acid level of 17 mg/dL. Which of the following drugs might have caused the symptoms and signs of this patient?Question 8Answera.Methyldopab.Furosemidec.Minoxidild.Prazosine.Hydrochlorothiazide
Question
A 52-year-old man complained to his physician of acute pain at the base of his right big toe. The man, who had been working as a painter for 15 years, was recently diagnosed with essential hypertension and started an antihypertensive therapy one month ago. A lab test showed a plasma uric acid level of 17 mg/dL. Which of the following drugs might have caused the symptoms and signs of this patient?Question 8Answera.Methyldopab.Furosemidec.Minoxidild.Prazosine.Hydrochlorothiazide
Solution
Para responder a esta pregunta, sigamos los siguientes pasos:
-
Identificar los síntomas y signos del paciente:
- Dolor agudo en la base del dedo gordo del pie derecho.
- Nivel de ácido úrico en plasma de 17 mg/dL (elevado).
-
Relacionar los síntomas con una posible condición médica:
- El dolor agudo en la base del dedo gordo del pie y el nivel elevado de ácido úrico son indicativos de gota.
-
Considerar la historia médica reciente del paciente:
- El paciente fue diagnosticado con hipertensión esencial y comenzó una terapia antihipertensiva hace un mes.
-
Identificar los medicamentos antihipertensivos que pueden elevar el ácido úrico:
- Algunos medicamentos antihipertensivos pueden aumentar los niveles de ácido úrico y precipitar un ataque de gota.
-
Revisar las opciones de medicamentos:
- a. Metildopa
- b. Furosemida
- c. Minoxidil
- d. Prazosina
- e. Hidroclorotiazida
-
Determinar cuál de estos medicamentos es conocido por elevar los niveles de ácido úrico:
- La hidroclorotiazida es un diurético tiazídico que puede aumentar los niveles de ácido úrico en el cuerpo y, por lo tanto, puede precipitar un ataque de gota.
Por lo tanto, la respuesta correcta es:
e. Hidroclorotiazida
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