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Context: Investigate the following claim: Stem cells may provide cures or effective treatments for many different medical conditions. • Develop your research question. To complete this task, you must • Identify the relevant scientific concepts associated with the claim. • Pose a research question addressing an aspect of the claim. • Conduct research to gather scientific evidence that may be used to address the research question and subsequently evaluate the claim. • Analyse the data to identify sufficient and relevant evidence • Identify any trends, patterns or relationships in the evidence. • Analyse the evidence to identify limitations • Interpret the evidence to construct justified scientific arguments. • Interpret the evidence to form a justified conclusion to the research question • Discuss the quality of the evidence. • Evaluate the claim by extrapolating the findings of the research question to the claim. • Suggest improvements and extensions to the investigation. • Communicate findings in an appropriate scientific genre. Scaffolding The response must be presented using an appropriate scientific genre (i.e. scientific report) and contain the following sections: RATIONALE • Discussion of how the research question was developed from the claim. • What background information was used to help develop the research question. • Define key terms • This section should be concluded with the testable/researchable research question. RESEARCH QUESTION: "How can stem cell therapy be utilised to develop effective treatments for chronic diseases such as Multiple Sclerosis? write a rationale Answer question

Question

Context: Investigate the following claim: Stem cells may provide cures or effective treatments for many different medical conditions. • Develop your research question. To complete this task, you must • Identify the relevant scientific concepts associated with the claim. • Pose a research question addressing an aspect of the claim. • Conduct research to gather scientific evidence that may be used to address the research question and subsequently evaluate the claim. • Analyse the data to identify sufficient and relevant evidence • Identify any trends, patterns or relationships in the evidence. • Analyse the evidence to identify limitations • Interpret the evidence to construct justified scientific arguments. • Interpret the evidence to form a justified conclusion to the research question • Discuss the quality of the evidence. • Evaluate the claim by extrapolating the findings of the research question to the claim. • Suggest improvements and extensions to the investigation. • Communicate findings in an appropriate scientific genre. Scaffolding The response must be presented using an appropriate scientific genre (i.e. scientific report) and contain the following sections: RATIONALE • Discussion of how the research question was developed from the claim. • What background information was used to help develop the research question. • Define key terms • This section should be concluded with the testable/researchable research question. RESEARCH QUESTION: "How can stem cell therapy be utilised to develop effective treatments for chronic diseases such as Multiple Sclerosis? write a rationale Answer question

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Solution

RATIONALE:

The claim that "Stem cells may provide cures or effective treatments for many different medical conditions" is a broad statement that encompasses a wide range of potential applications of stem cell therapy. To narrow down the scope of this investigation, the research question was developed to focus on a specific application of stem cell therapy: the treatment of chronic diseases, specifically Multiple Sclerosis (MS).

Multiple Sclerosis is a chronic disease that affects the central nervous system, causing a range of symptoms that can include fatigue, difficulty walking, numbness or tingling, muscle weakness and spasms, and problems with coordination and balance. Currently, there is no cure for MS, but treatments can help manage symptoms and reduce the progression of the disease.

Stem cells are cells with the potential to develop into many different types of cells in the body. They serve as a repair system for the body, replenishing adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm (the three germ layers)—but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.

The key terms in this research question are "stem cell therapy", "chronic diseases", and "Multiple Sclerosis". Stem cell therapy is a type of treatment that uses stem cells, or cells that come from stem cells, to replace or to repair a patient’s cells or tissues that are damaged. Chronic diseases are defined as conditions that last 1 year or more and require ongoing medical attention or limit activities of daily living or both. Multiple Sclerosis is a potentially disabling disease of the brain and spinal cord (central nervous system).

The research question that will guide this investigation is: "How can stem cell therapy be utilised to develop effective treatments for chronic diseases such as Multiple Sclerosis?" This question was chosen because it allows for an exploration of the potential applications of stem cell therapy in treating chronic diseases, using Multiple Sclerosis as a case study.

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develop a research question:Purpose Statement To analyse data in secondary sources and write a report in response to a current scientific claim Context Investigate the following claim: Stem cells may provide cures or effective treatments for many different medical conditions. Task • Gather secondary evidence related to a research question in order to evaluate the claim. Use scientifically credible sources, such as scientific journals, books by well-credentialed scientists and websites of governments, universities, independent research bodies or science and technology manufacturers. • Develop your research question. To complete this task, you must • Identify the relevant scientific concepts associated with the claim. • Pose a research question addressing an aspect of the claim. • Conduct research to gather scientific evidence that may be used to address the research question and subsequently evaluate the claim. • Analyse the data to identify sufficient and relevant evidence • Identify any trends, patterns or relationships in the evidence. • Analyse the evidence to identify limitations • Interpret the evidence to construct justified scientific arguments. • Interpret the evidence to form a justified conclusion to the research question • Discuss the quality of the evidence. • Evaluate the claim by extrapolating the findings of the research question to the claim. • Suggest improvements and extensions to the investigation. • Communicate findings in an appropriate scientific genre. Checkpoints Teacher Sighting/Signature Week 3 Select claim and develop research question Week 4 Identify sources, conduct research Week 5 Analyse and evaluate evidence. Submit draft Week 6 Submission of final response Authentication Strategies • Class time will be provided for task completion • You are to provide documentation of progress at indicated checkpoints (as above) • One draft will be collected and annotated by the teacher • All sources consulted will need to be acknowledged through in-text referencing and a reference list at the conclusion of the report. Scaffolding The response must be presented using an appropriate scientific genre (i.e. scientific report) and contain the following sections: RATIONALE • Discussion of how the research question was developed from the claim. • What background information was used to help develop the research question. • Define key terms • This section should be concluded with the testable/researchable research question. EVIDENCE • Discuss the quantitative and qualitative data available to support / refute the research question. • Analyse various sources of information • Link research findings directly to the research question. • Identify any relevant trends, patterns and relationships. EVALUATION • Present issues/limitations of the evidence considering the validity and reliability of the secondary sources cited. CONCLUSION • Include justified conclusions supported by evidence and linked to the research question. •

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