Which of the following neurological diseases is paired with the correct aetiology/pathogenesis/consequences?Question 4Select one:a.Progressive Bulbar Palsy (PBP) – intellectual disabilityb.Alzheimer's Disease – .Presence of Lewy bodies and reduced dopamine productionc.Spastic Cerebral Palsy - Involuntary, jerky movements and muscle hypotoniad.Parkinson's Disease – neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex).e.Epilepsy - Increased frequency or number of action potentials
Question
Which of the following neurological diseases is paired with the correct aetiology/pathogenesis/consequences?Question 4Select one:a.Progressive Bulbar Palsy (PBP) – intellectual disabilityb.Alzheimer's Disease – .Presence of Lewy bodies and reduced dopamine productionc.Spastic Cerebral Palsy - Involuntary, jerky movements and muscle hypotoniad.Parkinson's Disease – neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex).e.Epilepsy - Increased frequency or number of action potentials
Solution
The correct pairing is:
b. Alzheimer's Disease – Presence of Lewy bodies and reduced dopamine production
Here's why:
a. Progressive Bulbar Palsy (PBP) – intellectual disability: This is incorrect. PBP is a form of motor neuron disease, not associated with intellectual disability.
b. Alzheimer's Disease – Presence of Lewy bodies and reduced dopamine production: This is correct. Alzheimer's disease is characterized by the presence of Lewy bodies and reduced dopamine production.
c. Spastic Cerebral Palsy - Involuntary, jerky movements and muscle hypotonia: This is incorrect. Spastic cerebral palsy is characterized by muscle stiffness and weakness, not hypotonia or jerky movements.
d. Parkinson's Disease – neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex): This is incorrect. Parkinson's disease is characterized by the death of dopamine-generating cells in the substantia nigra, a region of the midbrain, not neurofibrillary tangles and cortical atrophy.
e. Epilepsy - Increased frequency or number of action potentials: This is incorrect. Epilepsy is characterized by recurrent, unprovoked seizures, which are caused by abnormal electrical activity in the brain, not necessarily an increased frequency or number of action potentials.
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