Which factors contribute to the activation of thrombin in the coagulation cascade, leading to the conversion of fibrinogen to fibrin and clot formation, and what regulatory mechanisms promote positive feedback of coagulation?Group of answer choicesFactors VII, VIII, IX, X, and XI; Feedback activation by thrombin.Factors IX, X, XI, XII, and XIII; Feedback inhibition by fibrin.Factors II, V, VIII, X, and XIII; Feedback inhibition by fibrin.Factors II, V, VII, X, and XII; Feedback activation by thrombin.

What does the coagulation factor that is deficient in Haemophilia A normally help generate?Group of answer choicesA thrombin burstA prothrombin burstA fibrin burstA fibrinogen burst

Coagulation can be activated by two different pathways, but both pathways converge on:Select one alternative:thrombinFactor XprothrombinFactor Xa

does the active x factor catalyses the conversion of fibrinogen to fibrin or prothrombin to thrombin

The extrinsic pathway of coagulation is activated by the:Group of answer choicesRelease of tissue factor due to injury.Activation of a proenzyme exposed to collagen.Conversion of prothrombin to thrombin.Sticking of platelets to damaged tissue.

The coagulation factor that is deficient in Haemophilia A normally circulates in an inactive form with which other factor?Group of answer choicesvon Willebrand Factor (vWF)Factor IIa (thrombin)Factor VFactor VIIIFactor IX