The extrinsic pathway of coagulation is activated by the release of tissue factor due to injury.

Here's a step-by-step explanation:

1. When there is an injury to the blood vessel, the cells around the injury site release a protein called tissue factor (TF).

2. This tissue factor binds with another protein in the blood called factor VII. This combination of tissue factor and factor VII triggers a series of reactions in the blood.

3. These reactions result in the activation of factor X, which is a crucial step in the coagulation process.

4. Activated factor X (along with other molecules) converts prothrombin, a protein present in the blood, into thrombin.

5. Thrombin then converts fibrinogen, another protein in the blood, into fibrin. Fibrin forms a mesh-like structure that traps blood cells and platelets, forming a clot and preventing further bleeding.

So, the initial trigger for the extrinsic pathway of coagulation is the release of tissue factor due to injury.

Question

The extrinsic pathway of coagulation is activated by the release of tissue factor due to injury.

Here's a step-by-step explanation:

1. When there is an injury to the blood vessel, the cells around the injury site release a protein called tissue factor (TF).

2. This tissue factor binds with another protein in the blood called factor VII. This combination of tissue factor and factor VII triggers a series of reactions in the blood.

3. These reactions result in the activation of factor X, which is a crucial step in the coagulation process.

4. Activated factor X (along with other molecules) converts prothrombin, a protein present in the blood, into thrombin.

5. Thrombin then converts fibrinogen, another protein in the blood, into fibrin. Fibrin forms a mesh-like structure that traps blood cells and platelets, forming a clot and preventing further bleeding.

So, the initial trigger for the extrinsic pathway of coagulation is the release of tissue factor due to injury.

Knowee AI · Accepted Answer

The extrinsic pathway of coagulation is activated by the release of tissue factor due to injury.

Here's a step-by-step explanation:

1. When there is an injury to the blood vessel, the cells around the injury site release a protein called tissue factor (TF).

2. This tissue factor binds with another protein in the blood called factor VII. This combination of tissue factor and factor VII triggers a series of reactions in the blood.

3. These reactions result in the activation of factor X, which is a crucial step in the coagulation process.

4. Activated factor X (along with other molecules) converts prothrombin, a protein present in the blood, into thrombin.

5. Thrombin then converts fibrinogen, another protein in the blood, into fibrin. Fibrin forms a mesh-like structure that traps blood cells and platelets, forming a clot and preventing further bleeding.

So, the initial trigger for the extrinsic pathway of coagulation is the release of tissue factor due to injury.

The extrinsic pathway of coagulation is activated by the:Group of answer choicesRelease of tissue factor due to injury.Activation of a proenzyme exposed to collagen.Conversion of prothrombin to thrombin.Sticking of platelets to damaged tissue.

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