During acute inflammation, the chemokines secreted by macrophages help to __________.reduce swellingpromote immune cell recruitmentreduce tissue damageprevent immune cell activation
Question
During acute inflammation, the chemokines secreted by macrophages help to __________.reduce swellingpromote immune cell recruitmentreduce tissue damageprevent immune cell activation
Solution
During acute inflammation, the chemokines secreted by macrophages help to promote immune cell recruitment.
Here's a step-by-step explanation:
-
Acute inflammation is the body's initial response to harmful stimuli such as injury or infection.
-
Macrophages, a type of white blood cell, play a crucial role in this process. They are among the first cells to arrive at the site of inflammation.
-
One of the ways macrophages contribute to the inflammatory response is by secreting substances called chemokines.
-
Chemokines are a type of cytokine, which are signaling molecules that mediate and regulate immunity, inflammation, and hematopoiesis.
-
The primary function of chemokines is to act as a chemoattractant to guide the migration of cells.
-
In the context of acute inflammation, the chemokines secreted by macrophages help to recruit more immune cells (like neutrophils and other macrophages) to the site of inflammation.
-
This recruitment is crucial for the body's defense against pathogens and for the removal of damaged tissue and cellular debris.
So, the correct answer is "promote immune cell recruitment".
Similar Questions
1. Chemotaxis is: a. Phagocytosis of infective agent. b. Rolling of leukocytes on endothelial surface. C. Adhesion of leukocytes to endothelium. d. Movement of extravasated neutrophils toward infective agent. 2. Which is FALSE about macrophages: a. They influence process of repair. b. After the end of inflammation they die and wander off into blood stream. C. They are derived from monocytes d. Capable of phagocytosis. 3. one of the following is an example of diffuse suppurative inflammation a. Carbuncle. b. Cellulitis. c. Boil. d. Abscess. 4. Pseudomembranous inflammation is: a. Mild form of acute suppurative inflammation. b. Caused by toxin producing bacterial c. Seen in serous cavities d. Caused by pyogenic bacteria. 5. By definition, granulomas are composed of: a. Cholesterol clefts. b. Endothelial cells and fibroblasts. c. Localized aggregation of activated macrophages. D. Hemosiderin-laden macrophages 6. Granulation tissue is: a. Avascular scar tissue. b. Occurs during early healing by regeneration. C. Pale& dry. d. Formed of fibroblasts & proliferating new capillaries. 7. All of the following can heal by regeneration EXCEPT: a. Liver cells. b. Endometrial lining. c. Nerve cells d. Hematopoietic cells. 8. In liver healing by fibrosis (liver cirrhosis) occurs if: a. Injury affects parenchymal cells only. b. Injury affects portal tracts only. c. Injury affects the peritoneal covering. d. Injury affects liver cells & the framework. 9. All of the following are complications of wound healing EXCEPT: a. Cosmetic deformity b. Carcinoma. c. Dermoid cyst. d. Chronic sinus 10. In acute inflammation TNF enhances: a. Redness and hotness. b. Expression of adhesion molecules on endothelium and inflammatory cells. c. Increase of vascular permeability. d. Pain. 11. Chemotactic factors include the following: a. Histamine. b. Prostaglandins. c. C5a. d. Lysosomal enzymes. 12. As regard the cellular events of acute inflammation: a. Neutrophils then monocytes accumulate within the extravascular space. b. The adhesion of neutrophils to the vascular endothelium at the sites of acute inflammation is called 'rolling' C. Integrin play a role in margination. d. Emigration of leucocytes is followed by leucopenia. 13. The key cells in chronic inflammation: a. Lymphocytes. b. Plasma cells. c. Macrophages. d. Eosinophils. 14. A sinus is: a. A local defect within a surface. b. A blind-ended tract. c. A tract communicating between two surfaces. d. Overdone repair. 15. PSA is a marker of: a. Nephroblastoma. b. Squamous cell carcinoma. C. Prostatic carcinoma. d. Granulosa cell tumour of ovary. 16. Aflatoxins are carcinogen for: a . Bronchogenic carcinoma. b. Renal cell carcinoma. c. Hepatocellular carcinoma. d. Urothelial carcinoma of the bladder. 17. Epstein-Barr virus is a cause the following tumor: a. Burkitt's lymphoma. b. Lung carcinoma. c. T cell lymphoma. d. Basal cell carcinoma.
__________ play a role in hematopoiesis and in activating adaptive and innate immune responses.ANSWERInterleukinsInterferonsTumor necrosis factorsChemokines
The swelling seen in an acute inflammatory response in a mild injury is mainly due to:Question 24Answera.the production of chemotactic factors by neutrophilsb.an increase in arteriolar vasodilationc.plasma (fluid) leaving the circulation and entering tissued.the production of fluid by fibroblastse.liquefactive necrosis due to bacterial action on tissue
What is the role of inflammation in response to damage?A. Increases mucosal secretions at the siteB. Fights pathogens that enter the bodyC. Provides a barrier for tissue from the outside environmentD. Creates swelling to help protect the site of damage
The name given to cytokines that recruit cells to move towards areas of inflammation is:
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.