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Analyze the following passage and answer the following questionsCase study: A girl of age 17 years suffers from polydypsea, polyphagia and polyurea. She is not ableto do her work because of weakness and pain in legs. Moreover she was continuously losing weightand body fat.On laboratory investigation, the following results were observedBLOOD EXAMINATION REPORTa. Glucose (random) – 294 mg/dlb. Glucose Fasting, plasma – 323 mg/dlc. HbA1c – 15.0%d. Estimated average Glucose – 395 mg/dlURINE TEST REPORT (Chemical examination)e. Ketones – positivef. Albumin – traceMicroscopic examinationCO5RBC – 10-15/HPFPus cells – 40-45/HPF

Question

Analyze the following passage and answer the following questionsCase study: A girl of age 17 years suffers from polydypsea, polyphagia and polyurea. She is not ableto do her work because of weakness and pain in legs. Moreover she was continuously losing weightand body fat.On laboratory investigation, the following results were observedBLOOD EXAMINATION REPORTa. Glucose (random) – 294 mg/dlb. Glucose Fasting, plasma – 323 mg/dlc. HbA1c – 15.0%d. Estimated average Glucose – 395 mg/dlURINE TEST REPORT (Chemical examination)e. Ketones – positivef. Albumin – traceMicroscopic examinationCO5RBC – 10-15/HPFPus cells – 40-45/HPF

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Solution

The passage describes a case study of a 17-year-old girl who is experiencing symptoms of polydipsia (excessive thirst), polyphagia (excessive hunger), and polyuria (excessive urination). She is also experiencing weakness and pain in her legs, and has been losing weight and body fat.

The laboratory investigation results are as follows:

BLOOD EXAMINATION REPORT: a. Glucose (random) - 294 mg/dl b. Glucose Fasting, plasma - 323 mg/dl c. HbA1c - 15.0% d. Estimated average Glucose - 395 mg/dl

URINE TEST REPORT (Chemical examination): e. Ketones - positive f. Albumin - trace

Microscopic examination: CO5RBC - 10-15/HPF Pus cells - 40-45/HPF

Based on these findings, we can draw the following conclusions:

  1. The random glucose level of 294 mg/dl and fasting plasma glucose level of 323 mg/dl indicate high blood sugar levels, which are indicative of diabetes.

  2. The HbA1c level of 15.0% further confirms the presence of uncontrolled diabetes. HbA1c is a measure of average blood sugar levels over the past 2-3 months.

  3. The estimated average glucose level of 395 mg/dl also supports the diagnosis of poorly controlled diabetes.

  4. The presence of ketones in the urine suggests that the body is breaking down fat for energy instead of using glucose, which is a sign of diabetic ketoacidosis.

  5. The trace amount of albumin in the urine indicates the presence of protein leakage, which can be a sign of kidney damage.

  6. The microscopic examination reveals the presence of red blood cells (CO5RBC) and pus cells in the urine, which may indicate an infection or inflammation in the urinary tract.

In summary, the girl in the case study is likely suffering from uncontrolled diabetes, specifically diabetic ketoacidosis, with possible kidney involvement. Further medical evaluation and treatment are necessary to manage her condition and alleviate her symptoms.

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