Treatment of endometriosis involves: a) Administration of gonadotrophins releasing hormone agonists to cause a pseudo- pregnancy b) Administration of gonadotrophins releasing hormone antagonists to cause a pseudo-menopause state c) Administration of large doses of oestrogens and androgens state to cause a pseudo pregnancy d) A and C above e) B and C above
Question
Treatment of endometriosis involves: a) Administration of gonadotrophins releasing hormone agonists to cause a pseudo- pregnancy b) Administration of gonadotrophins releasing hormone antagonists to cause a pseudo-menopause state c) Administration of large doses of oestrogens and androgens state to cause a pseudo pregnancy d) A and C above e) B and C above
Solution
The treatment of endometriosis involves:
a) Administration of gonadotrophin-releasing hormone (GnRH) agonists to cause a pseudo-pregnancy. This is because GnRH agonists suppress the production of estrogen by the ovaries, thereby reducing the growth of endometriosis.
b) Administration of gonadotrophin-releasing hormone antagonists to cause a pseudo-menopause state. Similar to GnRH agonists, GnRH antagonists also suppress the production of estrogen, but they do so by blocking the action of GnRH on the pituitary gland.
c) Administration of large doses of estrogens and androgens to cause a pseudo pregnancy is not a typical treatment for endometriosis. High levels of estrogen can actually stimulate the growth of endometriosis. Androgens, on the other hand, can have side effects such as weight gain, acne, and mood changes.
Therefore, the correct answer would be A and B, not D (A and C) or E (B and C).
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