1. A characteristic of a drug best suited for incorporation into an extended release product is: I, II and III. The drug should exhibit uniform absorption from the GIT, possess a good margin of safety, and ideally, should have either very slow or very fast absorption and excretion rates.

2. An attenuated organism is one that is: alive, able to multiply, but only able to produce mild disease. This is because the organism has been weakened to the point where it can no longer cause serious disease, but can still stimulate an immune response.

3. The treatment used to produce live attenuated vaccines is: Recombinant DNA technology. This technology allows for the manipulation of the organism's DNA to weaken it, thus creating a live attenuated vaccine.

4. The system composed of a core tablet surrounded by a semipermeable membrane coating having a 0.4 mm diameter hole produced by a laser beam is: Oral osmotic drug delivery system. This system allows for controlled release of the drug.

5. From the viewpoint of the pharmacist and patient, the solid dose formulations are more advantageous than liquid formulations due to: all of the reasons. They are stable, less reactive to containers, provide unit dose without need for separate containers, and have compactness and palatability.

6. The substance used to prevent drying of preparations, particularly in ointments and creams is: Ointment Base. This base helps to keep the preparation moist and prevents it from drying out.

7. The substance that can exhibit a reversible sol-to-gel or gel-to-sol transformation is: gels. This property allows gels to change their state with changes in temperature or other conditions.

8. All of the following activities are involved in the role of the nuclear pharmacist except: dispensing radiopharmaceuticals to patients. The role of a nuclear pharmacist typically involves compounding, storage, quality assurance, and procurement of radiopharmaceuticals, but not direct dispensing to patients.

Question

1. A characteristic of a drug best suited for incorporation into an extended release product is: I, II and III. The drug should exhibit uniform absorption from the GIT, possess a good margin of safety, and ideally, should have either very slow or very fast absorption and excretion rates.

2. An attenuated organism is one that is: alive, able to multiply, but only able to produce mild disease. This is because the organism has been weakened to the point where it can no longer cause serious disease, but can still stimulate an immune response.

3. The treatment used to produce live attenuated vaccines is: Recombinant DNA technology. This technology allows for the manipulation of the organism's DNA to weaken it, thus creating a live attenuated vaccine.

4. The system composed of a core tablet surrounded by a semipermeable membrane coating having a 0.4 mm diameter hole produced by a laser beam is: Oral osmotic drug delivery system. This system allows for controlled release of the drug.

5. From the viewpoint of the pharmacist and patient, the solid dose formulations are more advantageous than liquid formulations due to: all of the reasons. They are stable, less reactive to containers, provide unit dose without need for separate containers, and have compactness and palatability.

6. The substance used to prevent drying of preparations, particularly in ointments and creams is: Ointment Base. This base helps to keep the preparation moist and prevents it from drying out.

7. The substance that can exhibit a reversible sol-to-gel or gel-to-sol transformation is: gels. This property allows gels to change their state with changes in temperature or other conditions.

8. All of the following activities are involved in the role of the nuclear pharmacist except: dispensing radiopharmaceuticals to patients. The role of a nuclear pharmacist typically involves compounding, storage, quality assurance, and procurement of radiopharmaceuticals, but not direct dispensing to patients.

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