Which of the following compounds is not reactive toward a Friedel-Crafts reaction?Select answer from the options belowTolueneNitrobenzeneChlorobenzeneAnisoleBenzene Save for LaterSubmit Answer
Question
Which of the following compounds is not reactive toward a Friedel-Crafts reaction?Select answer from the options belowTolueneNitrobenzeneChlorobenzeneAnisoleBenzene Save for LaterSubmit Answer
Solution
The compound that is not reactive toward a Friedel-Crafts reaction among the options given is Nitrobenzene.
The reason is that Nitrobenzene has a strong electron-withdrawing nitro group (-NO2) attached to the benzene ring. This group deactivates the benzene ring and makes it less susceptible to electrophilic attack, which is a key step in the Friedel-Crafts reaction. Therefore, Nitrobenzene is generally unreactive in Friedel-Crafts reactions.
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