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Which of the following is most reactive in nucleophilic acyl substitution?Select answer from the options belowketoneacid halidecarboxylic acidester

Question

Which of the following is most reactive in nucleophilic acyl substitution?Select answer from the options belowketoneacid halidecarboxylic acidester

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Solution

The most reactive compound in nucleophilic acyl substitution is the acid halide. This is because the halide ion is a good leaving group, and the carbon of the carbonyl group in acid halides is highly electrophilic, making it very susceptible to attack by nucleophiles.

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