For normal replication of DNA in eukaryotes, which one of the following statements is most correct?Group of answer choicesA single strand copy of the leading strand is made first, and then a complementary strand is synthesised to form a new double helix. This is performed entirely by the enzyme DNA polymerase.In making two copies, each strand of the original DNA is used as a template (semiconservative replication). This is performed by DNA polymerase with assistance from several additional enzymes.In making two copies, each strand of the original DNA is used as a template (semiconservative replication). This is performed entirely by the enzyme DNA polymerase.A single strand copy of the leading strand is made first, and then a complementary strand is synthesised to form a new double helix. This is performed by DNA polymerase with assistance from several additional enzymes.
Question
For normal replication of DNA in eukaryotes, which one of the following statements is most correct?Group of answer choicesA single strand copy of the leading strand is made first, and then a complementary strand is synthesised to form a new double helix. This is performed entirely by the enzyme DNA polymerase.In making two copies, each strand of the original DNA is used as a template (semiconservative replication). This is performed by DNA polymerase with assistance from several additional enzymes.In making two copies, each strand of the original DNA is used as a template (semiconservative replication). This is performed entirely by the enzyme DNA polymerase.A single strand copy of the leading strand is made first, and then a complementary strand is synthesised to form a new double helix. This is performed by DNA polymerase with assistance from several additional enzymes.
Solution
The most correct statement is: "In making two copies, each strand of the original DNA is used as a template (semiconservative replication). This is performed by DNA polymerase with assistance from several additional enzymes."
Here's why:
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DNA replication in eukaryotes is semiconservative. This means that each strand of the original DNA molecule serves as a template for the synthesis of a new, complementary strand. This results in two copies of the DNA, each composed of one old (original) strand and one new strand.
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DNA polymerase is the main enzyme involved in DNA replication, but it doesn't work alone. It needs the help of several other enzymes. For example, helicase unwinds the double helix, single-strand DNA-binding proteins prevent the strands from reannealing, primase synthesizes a short RNA primer that DNA polymerase can extend, and ligase seals gaps in the newly synthesized DNA.
So, the statement that best describes this process is the one that mentions semiconservative replication and the involvement of several enzymes, not just DNA polymerase.
Similar Questions
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