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The upstroke li mb of the action potential in SA node cells in the cardiac muscle is inresponse to:A. Opening of voltage gated Na+ channels.B. Opening of Transient Ca 2 + channels.C. Opening of Longer lasting Ca 2+ channels.D. Opening of voltage gated K+ channels.E. Opening of voltage gated Na+ channels

Question

The upstroke li mb of the action potential in SA node cells in the cardiac muscle is inresponse to:A. Opening of voltage gated Na+ channels.B. Opening of Transient Ca 2 + channels.C. Opening of Longer lasting Ca 2+ channels.D. Opening of voltage gated K+ channels.E. Opening of voltage gated Na+ channels

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Solution

The upstroke limb of the action potential in SA node cells in the cardiac muscle is in response to:

C. Opening of Longer lasting Ca 2+ channels.

The action potential in SA node cells of the cardiac muscle is unique compared to other cells. The upstroke (or depolarization phase) of the action potential in these cells is primarily due to the opening of long-lasting (L-type) calcium channels, not sodium channels as in many other cells. These channels allow calcium ions to enter the cell, causing the inside of the cell to become more positive and triggering the action potential.

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