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A molecule enters a cell and creates pores in the inner mitochondrial membrane. How will ATP generation as a result of oxidative phosphorylation be affected? A.Increased, because the cell membrane is still complete and proton movement is increased.B.Increased, because ATP is required for cell function and this cell’s mitochondria will need to work harder.C.Decreased, because there is no available oxygen.D.Decreased, because the proton gradient will be dissipated.

Question

A molecule enters a cell and creates pores in the inner mitochondrial membrane. How will ATP generation as a result of oxidative phosphorylation be affected? A.Increased, because the cell membrane is still complete and proton movement is increased.B.Increased, because ATP is required for cell function and this cell’s mitochondria will need to work harder.C.Decreased, because there is no available oxygen.D.Decreased, because the proton gradient will be dissipated.

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Solution

The correct answer is D. Decreased, because the proton gradient will be dissipated.

Here's the step-by-step explanation:

  1. Oxidative phosphorylation is the process in which ATP (adenosine triphosphate) is formed as a result of the transfer of electrons from NADH or FADH2 to O2 by a series of electron carriers. This process takes place in the mitochondria.

  2. The inner mitochondrial membrane is crucial for oxidative phosphorylation because it is impermeable to ions, allowing a proton gradient to be established across it.

  3. This proton gradient is essential for ATP synthesis. The energy stored in the gradient is used to drive the synthesis of ATP from ADP and inorganic phosphate.

  4. If a molecule creates pores in the inner mitochondrial membrane, protons will leak back across the membrane without passing through ATP synthase, the enzyme that makes ATP.

  5. This leakage dissipates the proton gradient, reducing the amount of ATP that can be produced.

  6. Therefore, ATP generation as a result of oxidative phosphorylation will be decreased.

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