Which of the following phrases describes the process where a plasmid is integrated into the genome during allelic exchange?Selectable marker.Gene deletion.Homologous recombination.Single cross-over.
Question
Which of the following phrases describes the process where a plasmid is integrated into the genome during allelic exchange?Selectable marker.Gene deletion.Homologous recombination.Single cross-over.
Solution
The process where a plasmid is integrated into the genome during allelic exchange is described by the phrase "Homologous recombination."
Here's a step-by-step explanation:
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A plasmid, which is a small, circular piece of DNA, is introduced into a cell. This plasmid carries a gene of interest that we want to integrate into the cell's genome.
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The cell's machinery recognizes the plasmid DNA and the genomic DNA as similar or "homologous," because they have the same sequence of nucleotides in a particular region.
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The cell's machinery then cuts both the plasmid DNA and the genomic DNA at these homologous regions
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