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One of the targets of CDK is a phosphatase. What effect does the phosphorylation of this phosphatase have during the transition through the cell cycle?Group of answer choicesIt causes CDK to be dephosphorylated as part of a positive CDK/cyclin feedback mechanism.It causes CDK to be phosphorylated as part of a part of a negative CDK/cyclin feedback mechanism.It causes CDK to be dephosphorylated as part of a as part of a negative CDK/cyclin feedback mechanism.It causes CDK to be phosphorylated as part of a positive CDK/cyclin feedback mechanism. PreviousNext

Question

One of the targets of CDK is a phosphatase. What effect does the phosphorylation of this phosphatase have during the transition through the cell cycle?Group of answer choicesIt causes CDK to be dephosphorylated as part of a positive CDK/cyclin feedback mechanism.It causes CDK to be phosphorylated as part of a part of a negative CDK/cyclin feedback mechanism.It causes CDK to be dephosphorylated as part of a as part of a negative CDK/cyclin feedback mechanism.It causes CDK to be phosphorylated as part of a positive CDK/cyclin feedback mechanism. PreviousNext

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Solution

The phosphorylation of the phosphatase targeted by CDK during the transition through the cell cycle causes CDK to be dephosphorylated as part of a negative CDK/cyclin feedback mechanism. This is because phosphatases are enzymes that remove phosphate groups from proteins, including CDK. This dephosphorylation of CDK can inhibit its activity, thus acting as a negative feedback mechanism to regulate the cell cycle.

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Similar Questions

What role does the proteasome play in the regulation of the cell cycle?Group of answer choicesIt degrades ubiquitinated cyclin as part of a positive CDK/cyclin feedback mechanism.It degrades ubiquitinated CDK as part of a negative CDK/cyclin feedback mechanism.It degrades ubiquitinated cyclin as part of a negative CDK/cyclin feedback mechanism.It degrades ubiquitinated CDK as part of a positive CDK/cyclin feedback mechanism.

Mechanism of cdk regulation

Which statement is correct regarding CDK?Group of answer choicesPhosphorylation of Tyr-15 activates CDK.It contains a destruction box which allows it to be ubiquitinated by the DBRP.It is an enzyme that removes phosphate groups from other proteins.Phosphatases are required for the activation of CDK.

The breakdown of the nuclear envelope is due to the phosphorylation of which protein by a CDK?Group of answer choicesPhosphatasecyclinDBRPLamin

What is the effect of a double stranded break on the regulation of the cell cycle?Group of answer choicesThe pRB protein remains unphosphorylated, preventing the activation of E2F.CDK phosphorylation of the E2F protein inactivates the transcription factor.The dephosphorylating of CDK by the p21 protein inactivates the CDK.The p53 protein phosphorylates and activates p21.

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