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What is the remaining long-term issue associated with drug-eluting stents?Group of answer choicesInfectionThrombosisFibrosisRestenosis

Question

What is the remaining long-term issue associated with drug-eluting stents?Group of answer choicesInfectionThrombosisFibrosisRestenosis

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Solution

The remaining long-term issue associated with drug-eluting stents is Thrombosis.

Here's why:

  1. Drug-eluting stents are designed to prevent restenosis (re-narrowing of the artery after stent placement) by slowly releasing a drug that inhibits cell proliferation.

  2. However, the drug also delays the healing of the artery wall where the stent is placed. This can leave the metal stent exposed to blood flow for a longer period of time, increasing the risk of blood clotting at the site, a condition known as stent thrombosis.

  3. Stent thrombosis is a serious complication that can lead to heart attack or death. Therefore, patients with drug-eluting stents are typically required to take antiplatelet

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Which of the following is a risk factor for heart disease?Being overweightBeing underweightRegular exerciseLow cholesterol levels2In coronary heart disease:The heart beats too quicklyThe heart beats too slowlyThe heart valves do not work properlyThe arteries that supply blood to the heart muscle become narrow3Which of the following is a risk associated with fitting a stent?Blood lossRejectionThrombosis/blood clotRequires general anaesthetic 4Statins may be prescribed to anyone at risk of cardiovascular disease. They work by:Suppressing the immune systemReducing the production of cholesterol by the liverIncreasing the production of cholesterol by the liverBreaking down cholesterol5Doctors can operate and replace faulty heart valves. What is a disadvantage of using a mechanical rather than a biological valve? More likely to be rejected Requires anti-coagulation medicationDoes not last as longRequires a close tissue match6In heart transplant operations, what is an advantage of using a natural donor heart rather than an artificial heart?Less likely to be rejected Does not require life-long medicationLonger lastingGood availability

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Which of the following is a risk factor for heart disease?Regular exerciseBeing overweightBeing underweightLow cholesterol levels2In coronary heart disease:The arteries that supply blood to the heart muscle become narrowThe heart valves do not work properlyThe heart beats too slowlyThe heart beats too quickly3Which of the following is a risk associated with fitting a stent?RejectionThrombosis/blood clotRequires general anaesthetic Blood loss4Statins may be prescribed to anyone at risk of cardiovascular disease. They work by:Suppressing the immune systemReducing the production of cholesterol by the liverBreaking down cholesterolIncreasing the production of cholesterol by the liver5Doctors can operate and replace faulty heart valves. What is a disadvantage of using a mechanical rather than a biological valve? Requires anti-coagulation medicationDoes not last as longRequires a close tissue matchMore likely to be rejected 6In heart transplant operations, what is an advantage of using a natural donor heart rather than an artificial heart?Longer lastingLess likely to be rejected Good availabilityDoes not require life-long medication

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