Which theory of depression holds that depression is associated with underactivity at serotonergic synapses? Group of answer choicesNeuroplasticity theory of depression Monoamine theory of depression Biopsychosocial theory of depression All of the above

Briefly outline the monoamine theory of depression AND describe THREE potential problems with this theory.

Which of the following statements about the monoamine hypothesis of depression and the development of antidepressant treatments is most accurate? Group of answer choicesThe monoamine hypothesis has been conclusively proven, leading to the development of highly effective antidepressant treatments that target serotonin and norepinephrine receptors.While the monoamine hypothesis has guided the development of antidepressants, its limitations have become increasingly apparent, as many patients do not respond adequately to these medications.The monoamine hypothesis has been discredited, and current research on antidepressant treatments focuses exclusively on alternative mechanisms, such as the glutamatergic system.The development of novel antidepressant treatments has been hindered by the lack of effective animal models as our emotional system is based on different neurobiological mechanisms than those of animals.

Depression is classified as what type of mental disorder?Group of answer choicesPsychotic disorderAnxiety disorderPersonality disorderMood disorder

Select the correct statement(s).Group of answer choicesDopamine is involved in the pathogenesis of addiction and dependence.Apart from its enzymatic degradation, acetylcholine may also be taken up by the presynaptic terminal and get recycled.The effect of acetylcholine is terminated by the activity of the enzyme called acetylcholinesterase.Decreased functional availability of acetylcholine, serotonin, and glutamate has all been implicated in the pathogenesis of depression.

Which of the following neurotransmitters plays a major role in depression?  a. Endorphins  b. Serotonin  c. Acetylcholine  d. Morphine