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The sickle-cell anemia allele is maintained at relatively high frequencies in some human populations because Blank______.Multiple choice question.the beta-globin gene mutates very frequently in those populationsheterozygotes for the disease allele are resistant to malariathe beta-globin gene is not subject to natural selection

Question

The sickle-cell anemia allele is maintained at relatively high frequencies in some human populations because Blank______.Multiple choice question.the beta-globin gene mutates very frequently in those populationsheterozygotes for the disease allele are resistant to malariathe beta-globin gene is not subject to natural selection

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Solution

The correct answer is "heterozygotes for the disease allele are resistant to malaria".

This is because individuals who are heterozygous for the sickle-cell allele (meaning they have one copy of the normal allele and one copy of the sickle-cell allele) have a higher resistance to malaria. This is a classic example of balanced polymorphism - the sickle-cell allele causes a serious disease when two copies are present, but provides a survival advantage against malaria when only one copy is present. Therefore, in regions where malaria is prevalent, the sickle-cell allele is maintained at higher frequencies.

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