An 18-month-old boy is brought to the emergency department by his parents because of an episode of nonbilious vomiting 2 hours ago and a 2-day history of increased fussiness, periods of inconsolable crying, lethargy, and decreased appetite. The patient was diagnosed with enteroviral meningitis 1 month ago because of similar symptoms. He has a history of otitis media, bacterial sinusitis, and pneumonia during the past year. He was born at term via spontaneous vaginal delivery. Vaccinations are up-to-date. His 5-year-old sister has no history of serious illness. The patient is awake but crying. His temperature is 39.9°C (103.9°F) and pulse is 150/min. Physical examination shows a diffuse macular rash over the trunk; no lymphadenopathy is noted. Cardiopulmonary auscultation discloses clear breath sounds bilaterally and normal heart sounds. The abdomen is soft, nontender, and nondistended. Leukocyte count is 14,200/mm3 and platelet count is 245,000/mm3. Examination of cerebrospinal fluid obtained on lumbar puncture shows:Opening pressure 190 mm H2OGlucose 60 mg/dLProtein 71 mg/dLLeukocyte count 310 cells/μLErythrocyte count 3 cells/μLGram stain shows no organisms. Which of the following is the most likely diagnosis?

A 9-year-old child was taken to the emergency department by his father, who was concerned about his son's recent fever, rash, stiff neck, headache, and nausea. Which CNS infection is he suffering from based on his symptoms?Group of answer choicesBacterial encephalitisViral meningitisViral encephalitisBacterial meningitisNext

A patient had unprotected sex two months ago, and has been experiencing flu-like symptoms within the past week. You order an indirect ELISA test which confirms that the individual has been infected with .You are about to start your clinical nursing rotations and have to go for some routine tests. You are injected with some purified protein derivative and within 72 hours you have a red, raised lesion at the site of the injection. This confirms you have been exposed to .Your 13-year-old child received all routine vaccinations as an infant but has recently become very ill, having paroxysmal coughing with loud intakes of breath. The pediatrician took samples from the nose and throat that were subject to PCR analysis for rapid confirmation that your child has .You are a physician at an urgent care center. A patient comes in with a fever, severely swollen lymph nodes, white spots on the back of the tonsils, and difficulty swallowing. To save time, you do a rapid lateral flow immunochromatographic test which confirms your suspicion that the patient has .

What disease is being described here? It is a serious viral illness that can be fatal if there are complications, and most children are vaccinated against it.

A 9-month-old boy is brought to the immunology clinic for evaluation. Clinical history notes thatthe patient has a three-month history of recurrent bouts of otitis media, sinusitis,bronchopneumonia, and gastroenteritis. Serum protein electrophoresis reveals depressed levels ofall serum immunoglobulins.1. What is the most likely diagnosis?2. What is the genetic defect? State the molecular and cellular consequences.3. What organisms will likely be found in the patient’s respiratory tract? What organisms willlikely be found in the patient’s gastrointestinal tract?Over the next two years, the boy develops arthritis. Treatment with replacement immunoglobulinsrelieves the symptoms.4. What is the rationale for the intravenous immunoglobulin therapy?235. Refer to the patient’s pedigree. Identify the inheritance pattern.6. The female individuals could be affected by this condition under what circumstance?24NeoplasiaCase 1:A 62-year-old woman had her uterus removed for uterine prolapse and urinary incontinence. Apedunculated mass, 3 cm in diameter, was found inside the uterus, 5 cms from the internal os. Cutsections of the mass revealed solid, whorled, cream tan surface.Refer to slide #Guide Questions:1. Illustrate the tumor. Give your histopathological diagnosis and describe the microscopicfeatures.2. What feature/s in this tumor suggests that it is likely to be a benign neoplasm?253. What feature/s in this kind of tumor would lead a pathologist to think it may be a malignantneoplasm?

Which viral disease that most children are vaccinated against has symptoms that include fever and a red skin rash?