Which one of the following statements is INCORRECT about the events that occur when glucose enters a hepatocyteQuestion 14Select one:a.Insulin inhibits lipolysis.b.Glucose enters the hepatocyte through the GLUT2 transporter protein.c.Excess acetyl CoA can enter the lipogenesis pathway.d.Insulin receptor activation inhibits enzymes that allow glucose oxidation through glycolysis and the Kreb’s cycle.e.Glucose is converted into glucose-6-phosphate (G6P), glucose-1-phosphate (G1P), then glycogen because insulin receptor activity activates glucokinase and glycogen synthase enzymes, respectively.
Question
Which one of the following statements is INCORRECT about the events that occur when glucose enters a hepatocyteQuestion 14Select one:a.Insulin inhibits lipolysis.b.Glucose enters the hepatocyte through the GLUT2 transporter protein.c.Excess acetyl CoA can enter the lipogenesis pathway.d.Insulin receptor activation inhibits enzymes that allow glucose oxidation through glycolysis and the Kreb’s cycle.e.Glucose is converted into glucose-6-phosphate (G6P), glucose-1-phosphate (G1P), then glycogen because insulin receptor activity activates glucokinase and glycogen synthase enzymes, respectively.
Solution
The incorrect statement is:
d. Insulin receptor activation inhibits enzymes that allow glucose oxidation through glycolysis and the Kreb’s cycle.
This is incorrect because insulin receptor activation actually stimulates, not inhibits, the enzymes that allow glucose oxidation through glycolysis and the Kreb’s cycle. Insulin promotes glucose uptake and utilization by cells, and it does this by activating various enzymes involved in glucose metabolism.
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