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Which one of the following statements about the biochemical pathway for glucose-stimulated insulin secretion from the pancreas is INCORRECT?Question 4Select one:a.Glucose enters the pancreatic beta cell via GLUT2 transporters.b.The endoplasmic reticulum assists exocytosis of insulin from the beta cell.c.Glucose enters the pancreatic beta cell where it is used to fuel glycolysis and the Krebs cycle.d.Opened voltage-gated calcium channels are the only source of Ca2+ that triggers the release of insulin via exocytosis.e.ATP inhibits potassium (K+) channels on the cell membrane.

Question

Which one of the following statements about the biochemical pathway for glucose-stimulated insulin secretion from the pancreas is INCORRECT?Question 4Select one:a.Glucose enters the pancreatic beta cell via GLUT2 transporters.b.The endoplasmic reticulum assists exocytosis of insulin from the beta cell.c.Glucose enters the pancreatic beta cell where it is used to fuel glycolysis and the Krebs cycle.d.Opened voltage-gated calcium channels are the only source of Ca2+ that triggers the release of insulin via exocytosis.e.ATP inhibits potassium (K+) channels on the cell membrane.

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Solution

The incorrect statement is:

d. Opened voltage-gated calcium channels are the only source of Ca2+ that triggers the release of insulin via exocytosis.

This statement is incorrect because, while opened voltage-gated calcium channels do play a significant role in triggering the release of insulin, they are not the only source of Ca2+ that can do so. Intracellular stores of Ca2+ can also contribute to the triggering of insulin release.

This problem has been solved

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