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What two characteristics does an STR locus need to have to be useful in DNA fingerprinting?

Question

What two characteristics does an STR locus need to have to be useful in DNA fingerprinting?

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Solution

An STR (Short Tandem Repeat) locus needs to have two main characteristics to be useful in DNA fingerprinting:

  1. High Polymorphism: This means that the STR locus should have a high degree of variation among individuals. The more variation there is, the more likely it is that the STR pattern will be unique to each individual. This makes it easier to distinguish between different individuals' DNA.

  2. High Mutation Rate: STR loci should have a high mutation rate. This means that they change frequently from one generation to the next. This high mutation rate contributes to the high degree of polymorphism.

These two characteristics make STR loci ideal for DNA fingerprinting, as they allow for a high degree of individual identification.

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