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Which of the following neurological diseases is paired with the correct aetiology/pathogenesis/consequences?Question 26Select one:a.Epilepsy - Increased frequency or number of action potentialsb.Alzheimer's Disease – .Presence of Lewy bodies and reduced dopamine productionc.Progressive Bulbar Palsy (PBP) – intellectual disabilityd.Parkinson's Disease – neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex).e.Spastic Cerebral Palsy - Involuntary, jerky movements and muscle hypotonia

Question

Which of the following neurological diseases is paired with the correct aetiology/pathogenesis/consequences?Question 26Select one:a.Epilepsy - Increased frequency or number of action potentialsb.Alzheimer's Disease – .Presence of Lewy bodies and reduced dopamine productionc.Progressive Bulbar Palsy (PBP) – intellectual disabilityd.Parkinson's Disease – neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex).e.Spastic Cerebral Palsy - Involuntary, jerky movements and muscle hypotonia

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Solution

The correct pairing is a. Epilepsy - Increased frequency or number of action potentials.

Epilepsy is a neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain. This abnormal electrical activity can result in an increased frequency or number of action potentials.

The other options are incorrect because:

b. Alzheimer's Disease is characterized by the presence of amyloid plaques and neurofibrillary tangles, not Lewy bodies and reduced dopamine production.

c. Progressive Bulbar Palsy (PBP) is a disease that attacks the nerves controlling the muscles that enable talking, swallowing, chewing, and other functions. It does not cause intellectual disability.

d. Parkinson's Disease is characterized by the death of dopamine-generating cells in the substantia nigra, a region of the midbrain, not neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex).

e. Spastic Cerebral Palsy is characterized by increased muscle tone resulting in stiff and jerky movements, not involuntary, jerky movements and muscle hypotonia.

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