Which one of the following is used for global alignment of two protein sequences?(A) Chou-Fasman method(B) Garnier-Osguthorpe-Robson (GOR) method(C) Needleman-Wunsch algorithm(D) Smith-Waterman algorithm
Question
Which one of the following is used for global alignment of two protein sequences?(A) Chou-Fasman method(B) Garnier-Osguthorpe-Robson (GOR) method(C) Needleman-Wunsch algorithm(D) Smith-Waterman algorithm
Solution
The correct answer is (C) Needleman-Wunsch algorithm. This algorithm is specifically designed for global alignment of two protein sequences. It works by aligning the entire length of the sequences from start to end, which is why it's referred to as a global alignment method.
The Chou-Fasman method (A) and the Garnier-Osguthorpe-Robson (GOR) method (B) are both used for predicting secondary structure of proteins, not for sequence alignment. The Smith-Waterman algorithm (D) is used for local alignment of two protein sequences, not global alignment.
Similar Questions
What problem was addressed by Smith and Waterman (1981a,b) in their modification of the Needleman-Wunsch algorithm?a: Assessing the significance of alignment scoresb: Locating significant regions in DNA and protein sequencesc: Determining sequence identityd: Predicting protein structures
Global alignments are based on the Needleman–Wunsch algorithm True False
Which of the following tools can be used for local alignment: BLAST Clustal Omega Needleman–Wunsch algorithm KEGG
Which program is commonly used for aligning three or more sequences simultaneously?a: Needleman-Wunschb: Gibbs samplingc: PILEUPd: CLUSTALW
Which of the following is NOT used for generating an optimal alignment of twonucleotide sequences?(A) Gap penalties(B) Match scores(C) Mismatch scores(D) Nucleotide composition
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