In some cases, a single antimicrobial agent is not sufficient to destroy all the pathogens that develop during the course of a disease; thus, two or more drugs may be used simultaneously to kill all the pathogens and to prevent resistant mutant pathogens from emerging. In tuberculosis, for example, in which multidrug-resistant strains of Mycobacterium tuberculosis are frequently encountered, four drugs (isoniazid, rifampin, pyrazinamide, and ethambutol) are routinely prescribed, and as many as 10 drugs may be required for especially resistant strains.(1 Point)TrueFalse
Question
In some cases, a single antimicrobial agent is not sufficient to destroy all the pathogens that develop during the course of a disease; thus, two or more drugs may be used simultaneously to kill all the pathogens and to prevent resistant mutant pathogens from emerging. In tuberculosis, for example, in which multidrug-resistant strains of Mycobacterium tuberculosis are frequently encountered, four drugs (isoniazid, rifampin, pyrazinamide, and ethambutol) are routinely prescribed, and as many as 10 drugs may be required for especially resistant strains.(1 Point)TrueFalse
Solution
True
Similar Questions
These days, it is quite common to hear about drug-resistant bacteria, or “superbugs,” as they have been labeled by the press. Although “superbug” can refer to an organism that is resistant to only one antimicrobial agent, the term usually refers to multidrug resistant organisms (i.e., organisms that are resistant to more than one antimicrobial agent). Infections caused by superbugs are much more difficult to treat. It is important to note that bacteria are not the only microbes that have developed resistance to drugs. Certain viruses (including HIV, herpes simplex viruses, and influenza viruses), fungi (both yeasts and moulds), parasitic protozoa, and helminths have also developed resistance to drugs. Parasitic protozoa that have become drug-resistant include strains of P. falciparum, Trichomonas vaginalis, Leishmania spp., and Giardia lamblia.(1 Point)TrueFalse
Antibiotics are effective against:
The use of two antimicrobial agents to treat an infectious disease sometimes produces a degree of pathogen killing that is far greater than that achieved by either drug alone. This is known as synergism. Many urinary, respiratory, and gastrointestinal infections respond particularly well to a combination of trimethoprim and sulfamethoxazole, a combination referred to as co-trimoxazole; brand names include Bactrim and Septra. There are situations, however, when two drugs are prescribed (perhaps by two different clinicians who are treating the patient’s infection) that actually work against each other. This is known as antagonism. The extent of pathogen killing is less than that achieved by either drug alone. (1 Point)TrueFalse
How many different "lines" of antibiotics against TB are there?Multiple Choiceonetwothreefourfive or more
The following are broad spectrum drugs that act on bacteria by inhibiting it's protein synthesis(1 Point)Chloramphenicol, ketolides, mupirocin, tetracyclinesClindamycin, erythromycin and other macrolides, linezolid, streptograminsAminoglycosides, clindamycin, erythromycin and other macrolides,
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