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1 ptsAstronaut on the International Space Station (ISS) follow strict training and exercise regimes. Despite these training regimes, there is still noticeable change in the heart with a reduction in Heart Mass, including left ventricular mass, and enlarged left atrium. Which of the following are plausible contributing factors, and/or explanation for the observed changes in cardiac morphology?(select all that are correct, even if it is only one answer)Each correct answer will score partial points, each incorrect answer will score an equivalent deductionGroup of answer choicesThe lack of gravity directly affects cardiac myocytes resulting in atrophyThe lack of exercise results in less cardiac work loadThe observed reduction in systemic vascular resistance = lower afterloadThe lack of gravitational effect results in a lower afterload on the heart

Question

1 ptsAstronaut on the International Space Station (ISS) follow strict training and exercise regimes. Despite these training regimes, there is still noticeable change in the heart with a reduction in Heart Mass, including left ventricular mass, and enlarged left atrium. Which of the following are plausible contributing factors, and/or explanation for the observed changes in cardiac morphology?(select all that are correct, even if it is only one answer)Each correct answer will score partial points, each incorrect answer will score an equivalent deductionGroup of answer choicesThe lack of gravity directly affects cardiac myocytes resulting in atrophyThe lack of exercise results in less cardiac work loadThe observed reduction in systemic vascular resistance = lower afterloadThe lack of gravitational effect results in a lower afterload on the heart

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Solution

The correct answers could be:

  1. The lack of gravity directly affects cardiac myocytes resulting in atrophy: In the absence of gravity, the heart doesn't have to work as hard to pump blood throughout the body. This could lead to atrophy of the cardiac myocytes.

  2. The observed reduction in systemic vascular resistance = lower afterload: In space, the body's fluid distribution changes, which could lead to a reduction in systemic vascular resistance and thus a lower afterload on the heart.

  3. The lack of gravitational effect results in a lower afterload on the heart: Similar to the first point, the lack of gravity means the heart doesn't have to work as hard to pump blood, which could result in a lower afterload.

The statement "The lack of exercise results in less cardiac work load" might not be correct because astronauts follow strict exercise regimes while in space to counteract the effects of living in a microgravity environment.

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Astronaut on the International Space Station (ISS) follow strict training and exercise regimes. Despite these training regimes, there is still noticeable change in the heart with a reduction in Heart Mass, including left ventricular mass, and enlarged left atrium. Which of the following are plausible contributing factors, and/or explanation for the observed changes in cardiac morphology?(select all that are correct, even if it is only one answer)Each correct answer will score partial points, each incorrect answer will score an equivalent deductionGroup of answer choicesThe lack of gravity directly affects cardiac myocytes resulting in atrophyThe lack of exercise results in less cardiac work loadThe observed reduction in systemic vascular resistance = lower afterloadThe lack of gravitational effect results in a lower afterload on the heart

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