Which parameters are tested in pre-clinical trials?

In pre-clinical trials, several parameters are tested to ensure the safety and efficacy of a new drug or treatment. These parameters include:

1. Pharmacodynamics: This involves studying the effects of the drug on the body. It includes understanding how the drug interacts with its target in the body, the physiological effects it has, and how these effects change with dosage.

2. Pharmacokinetics: This involves studying how the body processes the drug. It includes understanding how the drug is absorbed, distributed, metabolized, and excreted by the body.

3. Toxicology: This involves studying the potential harmful effects of the drug. It includes understanding the drug's toxic effects on different organs, what doses these effects occur at, and whether these effects are reversible.

4. Dosage: This involves determining the optimal dosage of the drug. It includes understanding what dose is effective, what dose causes harmful effects, and how the dose should be adjusted based on factors like age, weight, and disease severity.

5. Efficacy: This involves studying whether the drug has the intended therapeutic effect. It includes understanding whether the drug can prevent, treat, or cure the disease it is intended for.

6. Safety: This involves studying whether the drug is safe for use. It includes understanding whether the drug causes any side effects, how severe these side effects are, and whether they outweigh the drug's therapeutic effects.

7. Stability: This involves studying how long the drug remains effective. It includes understanding how the drug is affected by factors like temperature, light, and humidity, and how long it can be stored before it starts to degrade.

These parameters are tested in pre-clinical trials to ensure that the drug is safe and effective before it is tested in