The major histocompatibility complex type I (MHC I) __________.ANSWERinteracts with CD4 on T helper cellsis found only on antigen-presenting cellsis found on all body cells except red blood cellspresents extracellular antigens
Question
The major histocompatibility complex type I (MHC I) __________.ANSWERinteracts with CD4 on T helper cellsis found only on antigen-presenting cellsis found on all body cells except red blood cellspresents extracellular antigens
Solution
The major histocompatibility complex type I (MHC I) is found on all body cells except red blood cells.
Here's a step-by-step explanation:
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The Major Histocompatibility Complex (MHC) is a set of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances. MHC proteins are found in all higher vertebrates.
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MHC I is one type of MHC protein that is present on all nucleated cells in the body. This means it is found on all body cells except for red blood cells, which do not have a nucleus.
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MHC I proteins present endogenous antigens (those generated within cells) to cytotoxic T cells. This is different from MHC II proteins, which present exogenous antigens (those from outside the cell) to helper T cells.
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MHC I does not interact with CD4 on T helper cells. Instead, MHC I interacts with CD8 on cytotoxic T cells.
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MHC I is not found only on antigen-presenting cells. As mentioned earlier, it is found on all nucleated cells in the body. Antigen-presenting cells, which include macrophages, dendritic cells, and B cells, do express MHC I, but they also express MHC II, which is not found on all cells.
Similar Questions
Which of the following cell types does not express MHC class I?Group of answer choiceserythrocytehepatocytelymphocytedendritic cellneutrophil
MHC class I is BEST DESCRIBED by which statement?Select one alternative:It presents viral peptides to CD8 T cells.It presents foreign peptides to CD4 T cells.It captures foreign peptides from extracellular pathogens.It is only expressed on specialised antigen presenting cells.
Major histocompatibility complex (MHC) proteins are also called human antigens (HLA).
Regarding the major histocompatibility class II (MHC II) molecule, which of the following statements is TRUE?Select one alternative:Each MHC II molecule can present only one specific (cognate) antigen.MHC II molecules present endogenous antigens, from within the cell.MHC II is expressed on all nucleated cells in the body.Antigenic peptides are anchored along the peptide binding groove in MHC II.
Class I MHC molecule can ____________.bind to CD8 molecules on T cellspresent antigens to B cellsbind to CD4 molecules on T cellsbind to antibodies
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