What is an apoenzyme?
Solution
An apoenzyme is the protein component of an enzyme, which requires a cofactor (either a coenzyme or a prosthetic group) to be fully functional. Here are the steps to understand this:
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Enzymes are biological catalysts that speed up chemical reactions in cells. They are typically proteins, but some RNA molecules can also function as enzymes.
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Most enzymes are composed of two parts - a protein component and a non-protein component. The protein component is known as the apoenzyme, while the non-protein component is known as the cofactor.
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The apoenzyme is inactive on its own. It requires the cofactor to be fully functional. The cofactor can be either a coenzyme (which is a small organic molecule, such as a vitamin or a derivative of a vitamin) or a prosthetic group (which is a non-protein molecule that is permanently attached to the enzyme).
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When the apoenzyme and the cofactor come together, they form the active enzyme, which is known as the holoenzyme. The holoenzyme is capable of catalyzing a chemical reaction.
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The apoenzyme provides the structure that allows the enzyme to bind to the substrate (the molecule that the enzyme acts upon), while the cofactor plays a role in the actual catalysis of the reaction.
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