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Genotypes of one pair of the following genes could benefit patients treated with warfarin.Question 9Answera.CYP2C9 and CYP2B1b.CYP2C19*2 and CYP2C9*3c.HLA-B∗1502 and CYP2D6d.CYP2C9 and VKORC1

Question

Genotypes of one pair of the following genes could benefit patients treated with warfarin.Question 9Answera.CYP2C9 and CYP2B1b.CYP2C192 and CYP2C93c.HLA-B∗1502 and CYP2D6d.CYP2C9 and VKORC1

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Solution

The genotypes that could benefit patients treated with warfarin are CYP2C9 and VKORC1.

Here's why:

Warfarin is an anticoagulant medication that is used to prevent blood clots. The dosage of warfarin needed can vary greatly between individuals and is influenced by many factors, including genetic factors.

CYP2C9 is a gene that encodes an enzyme involved in the metabolism of warfarin. Variations in this gene can affect how quickly an individual metabolizes warfarin, which can influence the dosage needed.

VKORC1 is a gene that encodes a protein targeted by warfarin. Variations in this gene can affect how sensitive an individual is to warfarin, which can also influence the dosage needed.

Therefore, knowing the genotypes of these two genes could help in determining the appropriate dosage of warfarin for an individual, potentially improving treatment outcomes and reducing the risk of side effects.

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